About us

History:

2001

Opening of laboratory facility to develop 3-D skin models using human primary cells

2002

Implementation of Quality Management System DIN ISO 9001:2008

2004

Launch of epidermal skin model EST-1000

2005

International ring trial for skin corrosivity testing according to OECD TG 431

2006

Submission of skin corrosivity dossier to ECVAM

2009

EST-1000 endorsed by ESAC as stand-alone method for skin corrosion according to OECD TG 431

2010

Installation of new class B clean rooms for mass skin model production

2011 

International ring trial for skin irritation testing according to OECD TG 439; Submission of skin irritation dossier to ECVAM

2013 

Introduction of the epiCS® family brand for the EST-1000 technology

epiCS®-M - launch of epidermal skin model with melanocytes

epiCS® - first commercial skin model - used in an integrated testing strategy (ITS) to address skin sensitization and potency

2014

epiCS® - new TG 431 including sub-categorization of corrosive chemicals

2016

ESAC opinion on epiCS® as a stand-alone method for skin irritation according to OECD TG 439

2017 / 2018

External Peer Review for epiCS® as a stand-alone method for skin irritation; accepted by WNT

2019

Final revision of OECD TG 439 adopted